Search on: NAV1.4 VOLTAGE-GATED SODIUM CHANNEL 
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Descriptor English:   NAV1.4 Voltage-Gated Sodium Channel 
Descriptor Spanish:   Canal de Sodio Activado por Voltaje NAV1.4 
Descriptor Portuguese:   Canal de Sódio Disparado por Voltagem NAV1.4 
Synonyms English:   NAV1.4 Voltage Gated Sodium Channel
NAV1.4 alpha Subunit
SCN4A Sodium Channel alpha Subunit
Sodium Channel, Voltage-Gated, Type IV, alpha 1 Subunit
Subunit, NAV1.4 alpha
Type 4 Voltage Gated Sodium Channel
Type 4 Voltage-Gated Sodium Channel
Voltage Gated Sodium Channel Type 4
Voltage Gated Sodium Channel Type 4 Subunit alpha
Voltage-Gated Sodium Channel Type 4
Voltage-Gated Sodium Channel Type 4 Subunit alpha
alpha Subunit, NAV1.4  
Tree Number:   D12.776.157.530.400.875.750.400
D12.776.210.500.675
D12.776.543.550.450.875.750.400
D12.776.543.585.400.875.750.400
Definition English:   A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of SKELETAL MYOCYTES. Defects in the SCN4A gene, which codes for the alpha subunit of this sodium channel, are associated with several MYOTONIC DISORDERS. 
Entry Combination - descr/qualif English:   NAV1.4 Voltage-Gated Sodium Channel/antagonists & inhibitors use Voltage-Gated Sodium Channel Blockers
NAV1.4 Voltage-Gated Sodium Channel/agonists use Voltage-Gated Sodium Channel Agonists
 
See Related English:   Hypokalemic Periodic Paralysis
Paralysis, Hyperkalemic Periodic
 
History Note English:   2013 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54950 
Unique Identifier:   D062553 

Occurrence in VHL: 		 

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